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    1. Cell Biology
    2. Immunology and Inflammation

    RAS-p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation

    Alejandro Rosell, Agata A Krygowska ... Esther Castellano
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid
    1. Developmental Biology
    2. Cancer Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun-Wai Suen ... Cristina Pina
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Structural Biology and Molecular Biophysics

    Simulation-based survey of TMEM16 family reveals that robust lipid scrambling requires an open groove

    Christina A Stephens, Niek van Hilten ... Michael Grabe
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Inadequate
    1. Neuroscience

    Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum

    Silas E Busch, Christian Hansel
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

    Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Integration of ATAC and RNA-sequencing identifies chromatin and transcriptomic signatures in classical and non-classical zebrafish osteoblasts and indicates mechanisms of entpd5a regulation

    Kleio Petratou, Martin Stehling ... Stefan Schulte-Merker
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    • Convincing
    1. Developmental Biology

    Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

    Adriana K Alexander, Karina F Rodriguez ... Humphrey Hung-Chang Yao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells

    Fangyuan Dong, Shan Zhang ... Shu-Heng Jiang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response

    Ling Cheng, Ian Meliala ... Mikael Björklund
    A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation mechanisms.
    1. Immunology and Inflammation

    A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome

    Yan Qian, Qiannv Liu ... Pengyan Xia
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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