226 results found
    1. Chromosomes and Gene Expression

    Non-canonical TAF complexes regulate active promoters in human embryonic stem cells

    Glenn A Maston et al.
    The transcription machinery used to regulate gene expression and self-renewal in human embryonic stem cells is different from that found in other cells.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex

    Tsutomu Aoki et al.
    A chromatin boundary factor that is only active during early embryo development has been discovered in Drosophila.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

    Anca M Farcas et al.
    A protein that can recognize regions of DNA with a high proportion of unmethylated CpG dinucleotides, and then recruit polycomb group proteins to these CpG islands, has been identified.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

    Hannah K Long et al.
    Islands of non-methylated DNA are shown to perform a similar epigenetic role in many different vertebrate species.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation

    Marc A Kerenyi et al.
    Lysine-specific demethylase 1 (Lsd1) has an essential role during both the early and later stages of blood cell development.
    1. Stem Cells and Regenerative Medicine
    2. Microbiology and Infectious Disease

    Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni

    Bo Wang et al.
    Cells that give rise to the infectious form of parasitic flatworms called schistosomes show similar patterns of gene expression to stem cells in free-living flatworms.
  1. Episode 3: August 2013

    Episode 3: August 2013

    In this episode we hear about the cocktail party effect, the role of psuedogene RNA in the immune response, the genetic origins of a common form of blindness, the flu vaccine, and the origins of schistosomiasis.

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