Rhythmic transcriptome analyses of human skeletal muscle tissue and cultured primary myotubes reveal an essential role for the circadian coordination of glucose homeostasis and lipid metabolism in human skeletal muscle.

Skeletal muscle organoids differentiated from human pluripotent stem cells offer a system for investigating myogenesis and satellite cell development with translational potential for muscular dystrophy modeling and therapy development.

The changes in the skeletal muscle proteome with age indicate the roots of the decline in muscle function with age.

A novel bioengineered human skeletal muscle model with accurate physiological and pharmacological responses may provide a useful tool for preclinical testing.

Using multiple genetic reporter system in human pluripotent stem cells, a transcriptional database for human early myogenesis has been established.

Novel human iPS cell derived and primary skeletal muscle stem cells show that abnormal ACVR1 activation increases osteogenic/ECM gene expression and impairs myofiber repair, while revealing muscle-specific regenerative properties.

Global proteomic and acetylomic analyses reveal how skeletal muscle adapts to high-intensity interval training including adaptations to processes regulating metabolism and contraction.

Genetic architecture of muscle secreted protein functions are dominated by sex.

The maintenance of skeletal muscle function improves the quality of life, and therefore understanding how changes in the genome drive changes in the skeletal muscle proteome has revealed novel regulators of muscle physiology.

Human skeletal muscle progenitors and motor neurons self-organize in three-dimensional co-culture to form functional neuromuscular junctions that developmentally mature from the embryonic to the adult state.