Machine learning models effectively predict the risk of post-stroke epilepsy using extensive clinical data, offering new insights for improving patient management in clinical neurology.
Jerome Robert, Emily B Button ... Cheryl L Wellington
Modelling beta-amyloid deposition in bioengineered human vessels represents a notable advance to further investigate the role of the vasculature in Alzheimer's disease.
The structural and functional analysis demonstrates the mechanism of dual functional, motility and microtubule depolymerization in a unique motor, KIF19A.
Virginia Folgado-Marco, Kristina Ames ... Nicholas E Baker
The homozygous and heterozygous phenotypes of mouse Rps12 deletion are described, highlighting pancytopenia reflecting roles in hematopoiesis and erythropoiesis.
Eva Lana-Elola, Sheona Watson-Scales ... Victor LJ Tybulewicz
A panel of seven new mouse strains with chromosomal duplications is used to identify a minimal genetic region required in three copies to cause congenital heart defects typical of human Down syndrome.
Kirsten A Donald, Mahmoud Maina ... Charles R Newton
Working in Africa provides neuroscientists with opportunities that are not available in other continents, but obstacles must be overcome for the neuroscience community in Africa to reach its full potential.
Basalins are intrinsically disordered proteins with astonishingly high-sequence divergence that are essential for building the transition zone basal plate and for proper central pair nucleation.