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    1. Neuroscience

    Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model

    Kevin P Koster, Walter Francesconi ... Akira Yoshii
    NMDA receptor function is regulated by protein depalmitoylation during visual cortical maturation and is dysfunctional in infantile neuronal ceroid lipofuscinosis.
    1. Neuroscience

    Reevaluating the Neural Noise Hypothesis in Dyslexia: Insights from EEG and 7T MRS Biomarkers

    Agnieszka Glica, Katarzyna Wasilewska ... Katarzyna Jednoróg
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Cestode larvae excite host neuronal circuits via glutamatergic signaling

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Computational and Systems Biology
    2. Neuroscience

    Fast and flexible sequence induction in spiking neural networks via rapid excitability changes

    Rich Pang, Adrienne L Fairhall
    Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.
    1. Neuroscience

    Biophysically inspired mean-field model of neuronal populations driven by ion exchange mechanisms

    Giovanni Rabuffo, Abhirup Bandyopadhyay ... Viktor K Jirsa
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    Myelin dystrophy impairs signal transmission and working memory in a multiscale model of the aging prefrontal cortex

    Sara Ibañez, Nilapratim Sengupta ... Christina M Weaver
    Biologically plausible levels of myelin dystrophy induce substantial working memory impairment in a computational model of brain aging across two spatial and temporal scales.
    1. Genetics and Genomics
    2. Neuroscience

    Orai-mediated calcium entry determines activity of central dopaminergic neurons by regulation of gene expression

    Rishav Mitra, Shlesha Richhariya, Gaiti Hasan
    Expression of the appropriate repertoire of membrane channels, essential for activity of flight-promoting central dopaminergic neurons of Drosophila, requires store-operated Ca2+ entry during late pupal development and early adults.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum

    Ya-Juan Wang, Xiao-Jing Di ... Ting-Wei Mu
    Hsp47 positively regulates the functional surface expression of endogenous GABAA receptors and plays a critical and general role in the maturation of Cys-loop neuroreceptors.
    1. Neuroscience

    SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

    Surya Chandra Rao Thumu, Monika Jain ... Narendrakumar Ramanan
    Serum response factor (SRF) deficient reactive astrocytes are neuroprotective in the mammalian brain.
    1. Neuroscience

    Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1

    Vincent Robert, Ludivine Therreau ... Rebecca Ann Piskorowski
    Input conveying social novelty information from the hypothalamus controls hippocampal activity by recruiting a novel inhibitory circuit in hippocampal area CA2.