Duplication of tumor suppressor genes contributed to the evolution of large, long-lived elephants.

Elephants escaped enhanced cancer susceptibility by evolving more master tumor suppressor genes.

Sloths, armadillos, and anteaters evolved genetic and cellular traits that make them remarkably cancer resistant.

A new computational tool provides insights into the structure of the cerebellum in mammals.

A rigorous and transparent evaluation of mesenchymal stem cell therapy for sepsis suggests it may be efficacious, although the strength of these findings is tempered by threats to validity in the studies that were included.

Two populations of serotonergic neurons are present in the medial and lateral hindbrain, which are shown to project to distinct spinal cord regions and have opposing effects on nociception in mice.

The new whale shark genome assembly represents the best gapless chondrichthyan genome assembly yet, and comparative genomic analyses provide insights into the evolution of vertebrate genome origins, immunity, and gigantism.

Hyperglycaemia increases influenza severity by damaging the pulmonary epithelial-endothelial barrier and increasing pulmonary oedema during Influenza A virus infection.

Protein kinase C brings about post-tetanic potentiation - a temporary increase in synaptic strength due to increased transmitter release - via phosphorylation of a target protein, Munc18-1.