2,853 results found
    1. Genetics and Genomics

    Mutations primarily alter the inclusion of alternatively spliced exons

    Pablo Baeza-Centurion et al.
    Deep mutagenesis reveals that mutations rarely alter the inclusion of highly-included exons.
    1. Neuroscience

    Decreased motor cortex excitability mirrors own hand disembodiment during the rubber hand illusion

    Francesco della Gatta et al.
    An illusion in which individuals feel that their own hand no longer belongs to them may reflect a temporary reduction in the brain’s ability to control the movement of the hand.
    1. Cell Biology
    2. Developmental Biology

    Philosophy of Biology: The analysis of living systems can generate both knowledge and illusions

    Antony M Jose
    By thinking about experimental techniques in terms of six broad approaches – perturbation, visualization, substitution, characterization, reconstitution, and simulation – researchers may be able to generate more reliable inferences.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis

    Blessy Paul et al.
    Chlamydia hijacks membrane trafficking proteins of the human host via the cytoplasmic domain of a secreted transmembrane protein.
  1. Meta-Research: A 10-year follow-up study of sex inclusion in the biological sciences

    Nicole C Woitowich et al.
    Sex-inclusive research practices have increased in many biological disciplines over the past decade, yet critical sex-based analyses and reporting have remained stagnant in most of these disciplines.
    1. Genetics and Genomics

    HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

    Jessica SY Ho et al.
    HNRNPM regulates exon inclusion and circularization events on transcripts of key homeostatic genes promoting cancer growth.
    1. Developmental Biology
    2. Neuroscience

    Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity

    Shinichiro Oku et al.
    Inclusion of a neuroligin alternatively spliced insert that interacts with a neurexin glycan modification promote development of functional synaptic connections between neurons and may help alleviate consequences of NLGN mutations.
    1. Neuroscience

    Stretching the skin immediately enhances perceived stiffness and gradually enhances the predictive control of grip force

    Mor Farajian et al.
    Elucidating the contribution of augmented artificial skin-stretch stimulation to the fingertips to the immediate illusion of a higher stiffness and to an increased predictive grip force control.
  2. Research Communication: Ways to increase equity, diversity and inclusion

    Devang Mehta et al.
    ​​ The eLife Early-Career Advisory Group calls for radical changes at eLife and other journals to make science more diverse and inclusive.
    Editorial
    Available as:
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    1. Neuroscience

    Pupillometry: Consciousness reflected in the eyes

    Woon Ju Park et al.
    People with higher autistic traits display stronger fluctuations in pupil size when presented with an optical illusion.
    Insight
    Available as:
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    • PDF

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