A novel image processing infrastructure that is capable of processing petascale datasets and can operate on both electron and light microscopy data.

A landmark-based cross-modality alignment method robust to variation in landmark sets is applied to annotate an EM time series of Caenorhabditis elegans embryonic development as a community resource.

Rhythmic centrifugal waves of auxin traveling through the tissue provides high definition positional information to cells that is not only spatial but also temporal.

3D serial electron microscopy reveals that individual dopamine axons in the nucleus accumbens contain different varicosity types based on their vesicle contents, rarely make synapses, and undergo major structural plasticity in response to cocaine.

New functionality in RELION-4.0 allows convenient structure determination from cryo electron tomography data to resolutions sufficient for de novo atomic modelling.

Compressing the actomyosin network by cortical flow causes filaments to align and form a constricting ring.

Wing transparency in mimetic butterflies and moths is achieved by an unexpected diversity of structural features, and both structures and light transmission properties of wings are under selection for convergence.

The structure and composition of the elusive vertex complex in Tectiviridae is finally revealed and the newly reported protein conformations help to maintain the capsid architecture.

Surface-based registration of the folded or unfolded human hippocampus achieves subfield alignment to within approximately 0.5 mm.

The structure of a large enzyme complex involved in methanogenesis was determined at high resolution by electron cryo-microscopy.