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    1. Computational and Systems Biology
    2. Neuroscience

    Bi-channel image registration and deep-learning segmentation (BIRDS) for efficient, versatile 3D mapping of mouse brain

    Xuechun Wang et al.
    A dual-channel image registration pipeline combined with deep-learning inference achieves accurate-and-flexible registration/segmentation/mapping of mouse brain.
    1. Plant Biology

    Accurate and versatile 3D segmentation of plant tissues at cellular resolution

    Adrian Wolny et al.
    Convolutional neural networks and graph partitioning algorithms can be combined into an easy-to-use tool for segmentation of cells in dense plant tissue volumes imaged with light microscopy.
    1. Cell Biology
    2. Computational and Systems Biology

    Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins

    Alex X Lu et al.
    100,000s of images from different growth conditions and genetic backgrounds can be integrated into proteome-scale analysis.
    1. Neuroscience

    An image-computable model for the stimulus selectivity of gamma oscillations

    Dora Hermes et al.
    Gamma-band oscillations show striking differences in stimulus selectivity compared to fMRI and broadband field potentials in human visual cortex, and are explained by a novel, image-computable model.
    1. Neuroscience

    Cortical excitability controls the strength of mental imagery

    Rebecca Keogh et al.
    Visual and prefrontal cortex excitability predict individual differences in visual imagery strength, and modulating excitability in these cortical regions causally alters the strength of visual imagery.
    1. Cell Biology
    2. Developmental Biology

    CytoCensus, mapping cell identity and division in tissues and organs using machine learning

    Martin Hailstone et al.
    Easy-to-use image analysis software enables single cell quantitation of cell types and division rates in complex 3D tissues including living Drosophila brains, mouse embryos and Zebrafish organoids.
    1. Structural Biology and Molecular Biophysics

    cisTEM, user-friendly software for single-particle image processing

    Timothy Grant et al.
    cisTEM enables fast processing of single-particle cryo-EM data on CPU-based workstations and is easily accessible to new users.
    1. Computational and Systems Biology
    2. Developmental Biology

    An image-based data-driven analysis of cellular architecture in a developing tissue

    Jonas Hartmann et al.
    A computational strategy for extracting representative numerical features from 3D microscopy data enables in-depth quantitative analysis of cell and tissue organization through machine learning-driven data integration and context-guided visualization.
    1. Neuroscience

    Reconstruction of natural images from responses of primate retinal ganglion cells

    Nora Brackbill et al.
    The visual message conveyed by retinal neurons to the brain when signaling natural scenes resembles the individual receptive fields only when viewed in context of the neuronal population.
    1. Neuroscience

    Predicting development of adolescent drinking behaviour from whole brain structure at 14 years of age

    Simone Kühn et al.
    Trajectories of adolescent drinking behavior between age 14 and 19 years can be predicted from bilateral striatal and cerebellar grey matter at 14 years of age.