214 results found
    1. Neuroscience

    A dual role for Cav1.4 Ca2+ channels in the molecular and structural organization of the rod photoreceptor synapse

    J Wesley Maddox et al.
    Ca2+ influx through Cav1.4 channels is required for the structural, but not the molecular organization of the rod photoreceptor synapse.
    1. Developmental Biology

    A multi-layered and dynamic apical extracellular matrix shapes the vulva lumen in Caenorhabditis elegans

    Jennifer D Cohen et al.
    Confocal imaging, electron microscopy, and genetic perturbations provide an unprecedented view of a complex and dynamic luminal matrix that determines tube shape during morphogenesis.
    1. Microbiology and Infectious Disease

    Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury

    Michelle M Lissner et al.
    Illustrating the impact of host metabolism on infection outcome, loss of the aryl hydrocarbon receptor in radioresistant cells leads to heme-mediated kidney toxicity during malaria.
    1. Evolutionary Biology
    2. Neuroscience

    The visual pigment xenopsin is widespread in protostome eyes and impacts the view on eye evolution

    Clemens Christoph Döring et al.
    The employment of xenopsin in ciliary and mixed microvillar/ciliary eye sensory cells in several protostome animals suggests high evolutionary plasticity of photoreceptors.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Pattern regulation in a regenerating jellyfish

    Chiara Sinigaglia et al.
    Clytia jellyfish regenerate body shape and organs through a mechanically driven process that coordinates tissue remodeling, localized proliferation, and precursor migration and promotes Wnt signaling at a muscle-based landmark.
    1. Neuroscience

    Ultra-high-field imaging reveals increased whole brain connectivity underpins cognitive strategies that attenuate pain

    Enrico Schulz et al.
    A single-trial whole-brain analysis of three cognitive strategies to attenuate pain shows that a more effective pain attenuation is associated with increased functional connectivity across the entire brain.
    1. Neuroscience

    Non-thalamic origin of zebrafish sensory nuclei implies convergent evolution of visual pathways in amniotes and teleosts

    Solal Bloch et al.
    Mesencephalic origin of the zebrafish thalamocortical-like visual projection neurons indicates independent evolution of tectofugal visual pathways in amniotes and teleosts.
    1. Plant Biology

    KATANIN-dependent mechanical properties of the stigmatic cell wall mediate the pollen tube path in Arabidopsis

    Lucie Riglet et al.
    KATANIN1 in stigma papilla cells prevents disordered pollen tube growth and straightens pollen tube direction, allowing the pollen tube to find its correct path to the underlying female tissues.
    1. Neuroscience
    Illustration of a hand and jigsaw puzzle

    Living Science: Theoretical musings

    Eve Marder
    The best theory papers help experimentalists to identify which of their results might be general and to plan a path through the maze of all possible future experiments.
    1. Microbiology and Infectious Disease

    Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration

    Malgorzata Broncel et al.
    Myristoylation of a secreted protein, identified in a global myristoylation analysis of the eukaryotic parasite Toxoplasma gondii, is important for host cell invasion.

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