The gene that allows budding yeast cells to switch their mating type evolved from a newly discovered family of genes named weird HO.

Applying big-data analytic techniques to brain images from 18,707 individuals is shedding light on the influence of aging on the brain.

In mice, deleting a long noncoding RNA drives premature aging.

A new device for isolating large quantities of old yeast cells expands the experimental boundaries of aging research.

Iodixanol provides an easy and affordable solution to a problem that has limited resolution and brightness when imaging living samples.

The poor reporting of imaging methods in the scientific literature is hindering the evaluation and replication of biomedical research.

The aged human auditory cortex shows preserved tonotopy, but temporal modulations are represented with a markedly broader tuning, highlighting decreased temporal selectivity as a hallmark of the aging auditory cortex.

Two novel subsets of microglia identified by their unique autofluorescence profiles differ in their subcellular organization, proteomic signatures and in their response to aging and lysosomal dysfunction.

Perceptual decision making, even in simple scenarios, is affected by sensory and decisional choice biases.

Establishment of two-photon imaging with a 1100-nm laser, which underfills the objective's back aperture, detects activity of multiple neurons in the prelimbic area and hippocampal CA1 region of the intact mouse brain.