5,502 results found
    1. Epidemiology and Global Health

    Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure

    Isabel Rodriguez-Barraquer, Emmanuel Arinaitwe ... Bryan Greenhouse
    Analyses of detailed clinical and entomological data from cohort studies reveal how anti-parasite and anti-disease immunity against P. falciparum develop as a function of age and transmission intensity.
    1. Ecology
    2. Evolutionary Biology

    CRISPR-based herd immunity can limit phage epidemics in bacterial populations

    Pavel Payne, Lukas Geyrhofer ... Jonathan P Bollback
    Bacteria can exhibit herd immunity protection against phages, which may play a significant role in their ecology and evolution.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Hybrid immunity from severe acute respiratory syndrome coronavirus 2 infection and vaccination in Canadian adults: A cohort study

    Patrick E Brown, Sze Hang Fu ... Ab-C Study Collaborators
    Population-level hybrid immunity depends substantially on vaccination coverage, including among those previously infected, and dried blood spot collection serves as a practicable biological surveillance platform for these immune responses.
    1. Ecology
    2. Microbiology and Infectious Disease

    Relationships between community composition, productivity and invasion resistance in semi-natural bacterial microcosms

    Matt Lloyd Jones, Damian William Rivett ... Thomas Bell
    Resident members of natural bacterial communities limit the growth of non-resident bacteria primarily by increasing overall community growth.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60

    Chun Kew, Wenming Huang ... Adam Antebi
    The splicing factor RNP-6/PUF60 suppresses immunity by modulating host splicing and transcriptional responses to infection.
    1. Cell Biology
    2. Genetics and Genomics

    NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling

    Malini Rajan, Cole P Anderson ... Elizabeth A Leibold
    Nuclear receptor NHR-14 regulates the subcellular localization of the zinc transcription factor PQM-1 to coordinate innate immunity with iron sequestration during pathogen infection in C. elegans..
    1. Immunology and Inflammation

    Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in end-stage renal disease (ESRD)

    Hee Young Kim, Yeon Jun Kang ... Won-Woo Lee
    Indoxyl sulfate, a key uremic toxin in chronic kidney disease (CKD), induces trained immunity in monocytes via crosstalk between aryl hydrocarbon receptor (AhR)-dependent epigenetic reprogramming by enhancement of the arachidonic acid pathway and AhR-independent metabolic rewiring.
    1. Evolutionary Biology

    Constitutive activation of cellular immunity underlies the evolution of resistance to infection in Drosophila

    Alexandre B Leitão, Ramesh Arunkumar ... Francis M Jiggins
    Single-cell transcriptomics of immune cells demonstrates that populations evolve inducible defences when infection rates are low and constitutive defences when infection is common.
    1. Ecology

    Environmental selection overturns the decay relationship of soil prokaryotic community over geographic distance across grassland biotas

    Biao Zhang, Kai Xue ... Yanfen Wang
    Environmental selection overwhelmed the geographic 'distance' effect when across biotas, overturning the previously well-accepted geographic pattern for microbes on a large scale.
    1. Plant Biology

    A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level

    Vilde Olsson Lalun, Maike Breiden ... Melinka A Butenko
    A molecular investigation on the role of the peptide ligand inflorescence deficient in abscission (IDA) in regulating immunity and development during cell separation in Arabidopsis thaliana.

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