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    1. Developmental Biology
    2. Neuroscience

    Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development

    Saman Hussain, Katherine Pinter ... Katie Kindt
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

    Michelle M Frank, Austen A Sitko ... Lisa V Goodrich
    Single-nucleus sequencing, anatomy, and physiology reveal heterogeneity among olivocochlear neurons (a group of cells that provide feedback to the inner ear), identify a neuropeptide-enriched subtype, and show that neuropeptide expression changes during postnatal development and after sound exposure.
    1. Neuroscience

    A projectome of the bumblebee central complex

    Marcel Ethan Sayre, Rachel Templin ... Stanley Heinze
    Serial-section electron microscopy uncovers the intricate neural network of the bumblebee central complex, revealing highly conserved projection patterns as well as novel circuit elements potentially unique to bees.
    1. Developmental Biology
    2. Neuroscience

    Multifunctional requirements for ERK1/2 signaling in the development of ganglionic eminence derived glia and cortical inhibitory neurons

    Sara J. Knowles, Michael C. Holter ... Jason M. Newbern
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience
    2. Evolutionary Biology

    A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma

    Mireia Rovira, Giuliano Ferrero ... Valérie Wittamer
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    Molecular and Mechanical Signatures Contributing to Epidermal Differentiation and Barrier Formation

    Alexandra Prado-Mantilla, Wenxiu Ning, Terry Lechler
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Cellular and circuit features distinguish dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation

    Laura Dovek, Krista Marrero ... Vijayalakshmi Santhakumar
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in Drosophila

    Céline Petitgas, Laurent Seugnet ... Serge Birman
    Purine recycling deficiency triggers metabolic and neurological defects reminiscent of Lesch–Nyhan disease in Drosophila, paving the way for studying this disorder and carrying out drug screening in an invertebrate organism.
    1. Cell Biology
    2. Neuroscience

    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

    Andrea Toledo, Mathieu Letellier ... Olivier Thoumine
    MDGAs are highly diffusive molecules that alter both neuroligin-1 and AMPA receptor dynamics and function, thereby significantly delaying the differentiation of excitatory post-synapses.
    1. Developmental Biology
    2. Neuroscience

    Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa

    Liyun Zhang, Conan Chen ... Jeff S Mumm
    Using a cross-species phenotypic drug discovery pipeline, compounds promoting rod photoreceptor survival in zebrafish and mouse models of retinitis pigmentosa were identified, evidence of additive effects of paired compounds and inhibition of PARP-dependent cell death suggest novel therapeutic strategies.