An in vivo electrophysiology approach identifies an incretin-like effect in Drosophila insulin-producing cells, highlighting key circuit dynamics which govern glucose homeostasis via conserved mechanisms.

Thousands of cell-type-specific split-GAL4 driver lines and a massive, searchable image collection enable Drosophila neuroscientists to target neurons of interest with increased precision.

A single amino acid change in a neuronal ion channel called KCNQ2 blocks ion flow, prevents protein localization on axons, and results in severe epilepsy and slowed neurological development.