A new autoencoder-based genotype imputation method shows superior accuracy across human genomes of diverse ancestry and across the allele-frequency spectrum, while delivering significantly faster inference run times relative to standard imputation tools.

Flight restrictions targeted at countries where SARS-CoV-2 variant-of-concern first emerged have limited effectiveness in deterring their introduction into the Netherlands due to the strength of regional travel importation risks in Europe.

Canadian COVID-19 travel restrictions imposed in March 2020 greatly reduced SARS-CoV-2 importations, but were insufficient to prevent new sublineages of similar transmissibility from being introduced and replacing early sublineages.

Human mobility drives malaria importation within countries and threatens elimination interventions, but can be measured using new approaches that combine parasite genetics, mobile phone data, travel surveys and models.

A new data imputation method that can be implemented quantumly allows for better and more reliable classifications.

The asymptomatic colonization and importation of methicillin-resistant Staphylococcus aureus (MRSA) in hospital settings can be inferred from observed cases using combined model-inference methods and used to inform improved interventions.

Genomic analysis of initial SARS-CoV-2 waves in Kenya revealed Mombasa City as a key gateway for variants entering Coastal Kenya with onward inter-county transmission highlighting significance of surveillance in major cities for early warning of lineages entering local populations.

Combining parasite genetic and human mobility data can provide detailed information on local and cross-border connectivity, allowing programs to strengthen local and regional coordination for successful elimination of malaria.

In large vaccine trials conducted in dengue-endemic Asia and Latin America, the CYD-TDV tetravalent dengue vaccine shows limited variation in intra-serotype efficacy in the target population for vaccination (>9 years).

A computational method and genome-wide scan of low-coverage single-cell sequencing data from a large sample of human sperm suggests balanced transmission of alleles to the gamete pool.