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Odor-identity dependent motor programs underlie behavioral responses to odors
Seung-Hye Jung et al.
Flies respond to odors by modulating multiple independently modulated motor programs.
Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves
Miriam Schwalm et al.
Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat
Hala Harony-Nicolas et al.
The production, validation and study of a novel rat model for Phelan McDermid Syndrome shows an ameliorative effect of oxytocin on both social and attentional deficits.
The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling
Kathryn P Harris et al.
Syntaxin 4 regulates retrograde signaling in the postsynaptic compartment at Drosophila synapses by controlling trafficking of Neuroligin and Synaptotagmin 4 cargo.
Structural Biology and Molecular Biophysics
Viral genome structures are optimal for capsid assembly
Jason D Perlmutter et al.
Computer simulations reveal that viral nucleic acids have an ideal structure for being packaged into outer protein shells called capsids.
Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats
Briac Halbout et al.
Inhibiting ventral tegmental dopamine neurons, or their inputs to nucleus accumbens, disrupts cue-motivated reward seeking in a manner that depends on the microstructure of behavior.
The readily-releasable pool dynamically regulates multivesicular release
Jada H Vaden et al.
The number of neurotransmitter vesicles released into the synaptic cleft is regulated by the size of the readily-releasable pool upstream of release probability.
Physics of Living Systems
Surface-to-volume scaling and aspect ratio preservation in rod-shaped bacteria
Nikola Ojkic et al.
Rod-shaped bacteria preserve their aspect ratios and surface-to-volume scaling by maintaining a homeostatic balance between the rates of cell elongation and division protein synthesis.
Predicting development of adolescent drinking behaviour from whole brain structure at 14 years of age
Simone Kühn et al.
Trajectories of adolescent drinking behavior between age 14 and 19 years can be predicted from bilateral striatal and cerebellar grey matter at 14 years of age.
Need-based prioritization of behavior
C Joseph Burnett et al.
A rich behavioral data set reveals the complex interactions and influence motivational systems have on one another, driving competition and optimal expression of behavior.
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