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    1. Cancer Biology
    2. Cell Biology

    Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

    Francesca Butera, Julia E Sero ... Chris Bakal
    A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.
    1. Developmental Biology
    2. Plant Biology

    Opposite polarity programs regulate asymmetric subsidiary cell divisions in grasses

    Dan Zhang, Roxane P Spiegelhalder ... Michael T Raissig
    The formation of stomatal 'helper cells' (=subsidiary cells) in grasses requires two opposing polarity domains with diverse roles in establishing division asymmetry.
    1. Neuroscience

    The influence of evidence volatility on choice, reaction time and confidence in a perceptual decision

    Ariel Zylberberg, Christopher R Fetsch, Michael N Shadlen
    A single framework of bounded evidence accumulation resolves the seemingly paradoxical effects of noise on accuracy, reaction time and confidence.
    1. Neuroscience

    An Information-Theoretic Approach to Reward Rate Optimization in the Tradeoff Between Controlled and Automatic Processing in Neural Network Architectures

    Giovanni Petri, Sebastian Musslick, Jonathan D. Cohen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Reaction times can reflect habits rather than computations

    Aaron L Wong, Jeff Goldsmith ... John W Krakauer
    Although reaction times are often assumed to reflect the time required to select and prepare a movement, they can be strongly influenced by prior experience.
    1. Neuroscience

    A General Framework for Characterizing Optimal Communication in Brain Networks

    Kayson Fakhar, Fatemeh Hadaeghi ... Claus C Hilgetag
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Ecology

    Travel fosters tool use in wild chimpanzees

    Thibaud Gruber, Klaus Zuberbühler, Christof Neumann
    Travel has a major influence on tool use in wild chimpanzees, suggesting that tool use reduced travel costs during hominid evolution.
    1. Evolutionary Biology
    2. Neuroscience

    The evolution and biological correlates of hand preferences in anthropoid primates

    Kai R Caspar, Fabian Pallasdies ... Sabine Begall
    Primate hand preference strength but not direction (left vs. right) generally reflects phylogeny and ecology at species level, but human handedness deviates markedly from all other species.
    1. Neuroscience

    Reproducibility of in vivo electrophysiological measurements in mice

    International Brain Laboratory, Kush Banga ... Ilana B Witten
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Dynamic decision policy reconfiguration under outcome uncertainty

    Krista Bond, Kyle Dunovan ... Timothy Verstynen
    A suspected change in action-outcome contingencies evokes a stereotyped response in the processes underlying a decision, resulting in a slow exploratory decision policy that gradually shifts to an exploitative policy as the environment remains stable.