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    1. Neuroscience

    Combining magnetoencephalography with magnetic resonance imaging enhances learning of surrogate-biomarkers

    Denis A Engemann, Oleh Kozynets ... Alexandre Gramfort
    Predicting age jointly from multimodal brain images and electrophysiology with machine learning enhances detecting health issues and facets of cognitive decline.
    1. Ecology

    Latent functional diversity may accelerate microbial community responses to temperature fluctuations

    Thomas P Smith, Shorok Mombrikotb ... Thomas Bell
    A novel species-sorting experiment finds that phylogenetically and functionally distinct microbial communities emerge under different temperature conditions due to the resuscitation of latent diversity.
    1. Neuroscience

    DeepPoseKit, a software toolkit for fast and robust animal pose estimation using deep learning

    Jacob M Graving, Daniel Chae ... Iain D Couzin
    A new deep-learning software toolkit with general-purpose methods for quickly and reliably measuring the full body posture of animals directly from images or videos without physical markers.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Molecular basis of the PIP2-dependent regulation of CaV2.2 channel and its modulation by CaV β subunits

    Cheon-Gyu Park, Wookyung Yu, Byung-Chang Suh
    The anchoring properties of CaV β2 subunits to the plasma membrane determine the biophysical states of CaV2.2 channels by regulating PIP2 coupling to the nonspecific phospholipid-binding site in the I–II loop.
    1. Ecology
    2. Evolutionary Biology

    Fin whale song evolution in the North Atlantic

    Miriam Romagosa, Sharon Nieukirk ... Mónica A Silva
    The rapid and gradual fin whale songs changes adopted by individuals of a certain area provide evidence of vocal learning in this species, elucidate patterns of song evolution and hints on the limits of song variation.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Computational prediction of CTCF/cohesin-based intra-TAD loops that insulate chromatin contacts and gene expression in mouse liver

    Bryan J Matthews, David J Waxman
    Certain types of 3D chromatin loops are easy to predict from existing or easily obtainable 2D information, which benefits gene expression studies in tissues/cells/organisms without extensive pre-existing 3D information.
    1. Neuroscience

    Valence biases in reinforcement learning shift across adolescence and modulate subsequent memory

    Gail M Rosenbaum, Hannah L Grassie, Catherine A Hartley
    Relative to children and adults, adolescents placed greater weight on negative prediction errors during learning and these age-varying learning idiosyncrasies biased subsequent memory for information associated with valenced outcomes.
    1. Neuroscience

    Dopamine neurons learn relative chosen value from probabilistic rewards

    Armin Lak, William R Stauffer, Wolfram Schultz
    When learning the reward probability of novel cues, dopamine neurons convey dissociable value and novelty signals.
    1. Neuroscience

    A neural network model of hippocampal contributions to category learning

    Jelena Sučević, Anna C Schapiro
    A neural network model of the hippocampus exhibits a division of labor across its two main pathways during category learning, with one pathway specializing in extracting systematic category information and another in encoding arbitrary details.
    1. Neuroscience

    Integrating prediction errors at two time scales permits rapid recalibration of speech sound categories

    Itsaso Olasagasti, Anne-Lise Giraud
    Keeping flexible adaptable representations of speech categories at different time scales allows the brain to maintain stable perception in the face of varying speech sound characteristics.