Ian A Clark, Siawoosh Mohammadi ... Eleanor A Maguire
A new magnetic resonance brain imaging measure reveals that variations in people’s ability to recall their past experiences may be related to the speed at which electrical signals travel along axons in the parahippocampal cingulum bundle.
Maria M Cobo, Caroline Hartley ... Rebeccah Slater
Measuring individual differences in noxious-evoked baseline sensitivity in neonates can substantially reduce sample sizes required in neonatal analgesic trials.
Philip Jean-Richard-dit-Bressel, Cassandra Ma ... Gavan P McNally
Behavioral analyses show that individuals insensitive to punishment are afraid of aversive events, they are simply unable to change their behaviour to avoid them.
Jadna Bogado Lopes, Anna N Senko ... Gerd Kempermann
When genes and environment are controlled, mice still develop stable differences in behavior, which are associated with large-scale differences in brain structure and connectivity.
Calcium imaging is used to construct a model of Caenorhabditis elegans nervous system dynamics capable of predicting future behavioral switches on a trial by trial basis and across individual animals.
Harriet Hunter, Dana de Gracia Hahn ... Jake P Mann
Animal studies of fatty liver disease over-estimate the benefit of drugs due to publication bias and are confounded by off-target weight loss, illustrating the challenge of successful translational across species.
Gail M Rosenbaum, Hannah L Grassie, Catherine A Hartley
Relative to children and adults, adolescents placed greater weight on negative prediction errors during learning and these age-varying learning idiosyncrasies biased subsequent memory for information associated with valenced outcomes.
David Duneau, Jean-Baptiste Ferdy ... Nicolas Buchon
An analysis of within-host bacterial proliferation reveals that minor "stochastic" variation in the ability of the innate immune response to control bacterial growth early on can result in either survival or death of the host.
Holly E Kinser, Matthew C Mosley ... Zachary Pincus
Expression of almost half of a library of fluorescent reporters distinguish long- from short-lived individual Caenorhabditis elegans, suggesting that organism-wide differences in gene expression drive future lifespan.
A novel animal model of economic decision-making captures complex patterns of choice behavior similar to those of humans, opening the way for mechanistic studies to probe the neural basis for this important form of executive function.
