94 results found
    1. Genetics and Genomics
    2. Immunology and Inflammation

    SCGN deficiency results in colitis susceptibility

    Luis F Sifuentes-Dominguez et al.
    A novel mutation in SCGN is associated with risk for inflammatory bowel disease and implicates the intestinal neuroendocrine compartment in the pathogenesis of this disorder.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling

    Phi Luong et al.
    Inflammatory bowel disease risk-gene, INAVA and the ARF-GEF ARNO, regulates non-canonical cortical actin assembly and IL-1b signaling to maintain epithelial homeostasis.
    1. Microbiology and Infectious Disease

    Gut microbiota density influences host physiology and is shaped by host and microbial factors

    Eduardo J Contijoch et al.
    The density of the gut microbiota influences the host immune system and adiposity, and can be therapeutically manipulated.
    1. Immunology and Inflammation

    Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

    Naresh S Redhu et al.
    A detailed time-series analysis reveals that the interleukin-10 receptor prevents susceptibility to microbiota-driven colonic inflammation that emerges at the time of weaning by directly inhibiting the acquisition of a pro-inflammatory intestinal macrophage phenotype.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Parkinson’s Disease: Linking mitochondria to the immune response

    Rebecca L Wallings et al.
    A gene associated with Parkinson’s disease regulates mitochondrial homeostasis, thus affecting innate immunity.
    Insight
    Available as:
    • HTML
    • PDF
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Microbiome: Does disease start in the mouth, the gut or both?

    Andrei Prodan et al.
    Oral bacteria colonize the gut more frequently than previously thought.
    Insight
    Available as:
    • HTML
    • PDF
    1. Immunology and Inflammation

    Microbiota: A gut feeling about arthritis

    Diane Mathis
    Insight
    Available as:
    • HTML
    • PDF
    1. Cell Biology
    2. Immunology and Inflammation

    Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1

    Maria-Bernadette Madel et al.
    Osteoclasts emerging in inflammation are heterogeneous and encompass a strongly inflammatory subset with a high resorbing activity and an immune suppressive subset that are able to control each other.
    1. Immunology and Inflammation

    Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

    Juan L Mendoza et al.
    Potential for specific microbiome-directed, MHC-restricted shaping of a commonly selected HIV-specific CD8+ T cell population was suggested by MHC class I yeast display-based peptide screening approaches.
    1. Neuroscience

    Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids

    Xin-Yan Zhang et al.
    Exogenous opioid analgesia is mediated by MORs expressed in glutamatergic neurons, whereas endogenous opioid analgesia is mediated by MORs expressed in GABAergic neurons.

Refine your results by:

Type
Research categories