4,779 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    ATPase activity of the DEAD-box protein Dhh1 controls processing body formation

    Christopher Frederick Mugler et al.
    The ATPase Dhh1 controls processing body formation and disassembly in yeast cells, and processing body dynamics can be recapitulated in vitro with recombinant Dhh1, ATP and RNA.
    1. Ecology

    Genomic adaptations in information processing underpin trophic strategy in a whole-ecosystem nutrient enrichment experiment

    Jordan G Okie et al.
    Trait-based metagenomic analysis of an ecosystem fertilization experiment shows that genomic traits that affect the costs and rates of biochemical information-processing mediate community assembly.
    1. Neuroscience

    Short-term plasticity at cerebellar granule cell to molecular layer interneuron synapses expands information processing

    Kevin Dorgans et al.
    Molecular, structural and functional diversity of cerebellar granule cell inputs on single molecular layer interneurons extends information processing in feed-forward inhibition microcircuits.
    1. Neuroscience

    Local processing in neurites of VGluT3-expressing amacrine cells differentially organizes visual information

    Jen-Chun Hsiang et al.
    Neurite arbors of VGluT3-expressing amacrine cells (VG3-ACs) process visual information locally uniformly detecting object motion while varying in contrast preferences; and in spite of extensive overlap between arbors of neighboring cells population activity in the VG3-AC plexus encodes stimulus positions with subcellular precision.
    1. Neuroscience

    Distinct lateral inhibitory circuits drive parallel processing of sensory information in the mammalian olfactory bulb

    Matthew A Geramita et al.
    Distinct lateral inhibitory circuits affect spiking in olfactory bulb mitral and tufted cells differently, which ultimately allows each cell type to best discriminate between similar odors in separate concentration ranges.
    1. Neuroscience

    Visual processing of informative multipoint correlations arises primarily in V2

    Yunguo Yu et al.
    Building on recent findings that central sensory processing allocates resources according to the informativeness of statistical features (Hermundstad et al., 2014), we identify visual area V2 as the site of the relevant computations for local image statistics, thus providing a common underpinning for diverse aspects of its neuronal selectivity.
    1. Neuroscience

    Cortical network architecture for context processing in primate brain

    Zenas C Chao et al.
    Large-scale electrocorticography and big data analysis of brain-wide neuronal interactions reveal the architecture of network information flow for context processing in primate brain.
    1. Neuroscience

    Nonlinear circuits for naturalistic visual motion estimation

    James E Fitzgerald, Damon A Clark
    New computational models provide insights into how the insect brain estimates the speed and direction of movement.
    1. Medicine
    2. Microbiology and Infectious Disease

    Early prediction of level-of-care requirements in patients with COVID-19

    Boran Hao et al.
    Using data for 2566 COVID-19 patients from five hospitals, models are developed to predict for each patient hospitalization and critical care needs, based on demographics, comorbidities, medications, and laboratory findings.
    1. Cell Biology

    p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition

    Senthil K Radhakrishnan et al.
    The enzyme p97/VCP regulates the activity of the transcription factor Nrf1 to promote increased transcription of genes that encode proteasome subunits following inhibition of the proteasome.

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