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Chromosomes and Gene Expression
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
Yuan Zhang, Yang Xie ... David J Mangelsdorf
Transgenic mice with high levels of FGF21 live for longer than wild-type mice and do so without reducing food intake.
Cell Biology
Cell Biology: New twists in the unfolded protein response
Benedict C S Cross, David Ron
Chromosomes and Gene Expression
Longevity: Could a hormone point the way to life extension?
Cynthia Kenyon
Cell Biology
Immunology and Inflammation
Sequence specific detection of bacterial 23S ribosomal RNA by TLR13
Xiao-Dong Li, Zhijian J Chen
A pattern recognition receptor called toll-like receptor 13 detects pathogens in a manner that is different to that seen in other pathogen sensors.
Immunology and Inflammation
Microbiology and Infectious Disease
Antibacterial Response: Histones join the fight against bacteria inside cells
Roberto Kolter
Immunology and Inflammation
Microbiology and Infectious Disease
A novel role for lipid droplets in the organismal antibacterial response
Preetha Anand, Silvia Cermelli ... Steven P Gross
Histones bound to lipid droplets inside cells offer protection against bacteria in flies, and possibly mice, thus suggesting a possible new innate immunity pathway.
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