300 results found
    1. Neuroscience

    Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure

    Jocelyn M Richard et al.
    Reward-related cues elicit phasic changes in activity in ventral pallidum neurons, which predict and functionally contribute to the speed of behaviors trained on the basis of act-outcome, but not stimulus-outcome, contingencies.
    1. Neuroscience

    A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories

    Ana C Sias et al.
    The bidirectional orbitofrontal cortex-basolateral amygdala circuit helps us to learn the details of predicted rewarding events and then to use that information to make good reward pursuit decisions.
    1. Neuroscience

    Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

    Jordan G McCall et al.
    Selective activation of locus coeruleus noradrenergic terminals drives anxiety-like behaviors through activation of β-adrenergic receptors in the basolateral amygdala.
    1. Neuroscience

    Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency

    Richard B Crouse et al.
    The release of acetylcholine in the basolateral amygdala is precisely timed to salient events during reward learning but has long-lasting effects that potentiate learning of cue-reward contingencies.
    1. Neuroscience

    Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats

    Briac Halbout et al.
    Inhibiting ventral tegmental dopamine neurons, or their inputs to nucleus accumbens, disrupts cue-motivated reward seeking in a manner that depends on the microstructure of behavior.
    1. Neuroscience

    Classical conditioning drives learned reward prediction signals in climbing fibers across the lateral cerebellum

    William Heffley, Court Hull
    Cerebellar climbing fibers can generate learned reward-predictive instructional signals, suggesting a role for cerebellar learning in the reinforcement of reward-driven behaviors.
    1. Neuroscience

    Orbital frontal cortex updates state-induced value change for decision-making

    Emily T Baltz et al.
    Orbital frontal cortex projection neuron activity is necessary to update state-dependent value change to control model-based behavior.
    1. Neuroscience

    Punishment insensitivity emerges from impaired contingency detection, not aversion insensitivity or reward dominance

    Philip Jean-Richard-dit-Bressel et al.
    Behavioral analyses show that individuals insensitive to punishment are afraid of aversive events, they are simply unable to change their behaviour to avoid them.
    1. Neuroscience

    Striatal direct and indirect pathway neurons differentially control the encoding and updating of goal-directed learning

    James Peak et al.
    Direct and indirect pathway neurons in posterior dorsomedial striatum were found to play distinct roles, with the former necessary for encoding and the latter for updating goal-directed learning.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimating SARS-CoV-2 seroprevalence and epidemiological parameters with uncertainty from serological surveys

    Daniel B Larremore et al.
    Integrating over multiple forms of statistical uncertainty associated with serological surveys can improve serosurvey design while also enabling that uncertainty to be appropriately propagated through epidemiological models.

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