1,009 results found
  1. December 2015

    Episode 26: December 2015

    In this episode we hear about heat-seeking behaviour in mosquitos, mass spawning in coral reefs, social organization in ants, fear in rats and tissue regeneration in newts.
  2. The cone snail Conus geographicus eating a goby fish

    Episode 55: March 2019

    In this episode, we hear about fast-acting insulin in cone snails, the roots of addiction, new gene editing techniques and gender biases in joint first authors.
  3. Episode 46: March 2018

    In this episode, we hear about autism, insulin resistance, Sci-Hub, coping with low levels of oxygen, and how the brain responds to blindness.
  4. April 2014

    Episode 11: April 2014

    In this episode we hear about neuropathic pain, gene therapy, insulin production, aging in worms, and how flatworms grow new body parts.
  5. Episode 45: February 2018

    In this episode, we hear about disease control in insects, placental development, post-traumatic stress disorder, the mission to create a human cell atlas and how crickets amplify their song.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

    Joseph JE Caesar et al.
    Genetic susceptibility to an infectious disease is linked to competition for binding a molecule on the bacterial surface by two host proteins with opposing roles in host immunity.
    1. Cell Biology
    2. Genetics and Genomics

    Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX

    Jiajia Ma et al.
    The serine protease Matriptase orchestrates simultaneous epithelial cell motility and inflammation in pathological states through respective activation of the MAPK pathway and generation of hydrogen peroxide.
    1. Cell Biology

    Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity

    Joseph A Giovinazzo et al.
    Cytotoxicity associated with APOL1 renal-risk variants occurs through its plasma-membrane localization, where aberrant channel activity drives a sustained sodium and calcium influx leading to cell swelling and eventually cell death.
    1. Plant Biology

    Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata

    Min Diao et al.
    Cytological and biochemical analyses reveal Arabidopsis formin 2 is involved in regulating PD permeability by anchoring actin filaments to PD and stabilizing them through actin filament barbed end capping activity.
    1. Cancer Biology

    A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

    Joanna L Gillis et al.
    A positive feedback loop between the androgen receptor and a key pentose phosphate pathway enzyme, 6PGD, in prostate cancer promotes tumour cell proliferation, survival and intracellular redox control.

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