Protein nutritional requirements decrease predictively with mass throughout ontogeny across the animal kingdom.

Genetically diverse rats reveal a single underlying construct linking key addiction-like behaviors, challenging compulsivity as an independent measure, and offering a new perspective on vulnerability and resilience to addiction.

A machine learning model could accurately estimate daily salt consumption in the general population and can be applied to countries lacking urine sample to compute the mean salt consumption at the population level.

Manipulating the activity of ‘stretch-sensitive’ ion channels in neurons innervating the digestive system of fruit flies has dramatic effects on food intake, suggesting that these ion channels could be targets for drugs to help tackle obesity.

Connectomic analysis demonstrates that a brain circuit, that may be conserved between flies and mammals, uses both fast synaptic transmission as well as peptidergic neuromodulation to connect chemosensory and endocrine systems.

Brain imaging and behavioral analysis reveal two opposing states of hunger, represented by anti-correlated lateral and caudal hypothalamic dynamics that are important for the homeostatic control of feeding in zebrafish.

The gut microbe-derived metabolite trimethylamine (TMA) is elevated in patients with alcohol-associated hepatitis and inhibition of the gut microbial enzymes that produce TMA may serve as a tractable therapeutic strategy for the treatment of ethanol-induced liver injury.

Cell type-specific transcriptomics in energy homeostasis neurons has identified hundreds of genes and multiple signaling pathways that are regulated by weight loss in mice, as well as several previously unexamined genes that can regulate appetite and body weight.

Greater mouse-eared bats prefer to hunt large ground insects despite high failure rates, but switch to smaller, easily caught flying insects in response to environmental changes.

tTARGIT AAVs offer a new approach to manipulate intersectional populations that produce selective and robust transgene expression and are easily modified.