Dot1l and its H3K79 methyltransferase activity are required for thermogenesis, and Dot1l is recruited by Zc3h10 to its targets genes to alter chromatin accessibility to activate the thermogenic gene program.

Neurite arbors of VGluT3-expressing amacrine cells (VG3-ACs) process visual information locally uniformly detecting object motion while varying in contrast preferences; and in spite of extensive overlap between arbors of neighboring cells population activity in the VG3-AC plexus encodes stimulus positions with subcellular precision.

The regulation of tfap2α expression by adam13 is essential during cranial neural crest cell migration in Xenopus laevis.

MT plus-end-mediated recruitment of a cortical pool of ECT2 trigger RhoA activation upon contact, which results in localized contractility during cytokinesis.

Interaction of oncoprotein transcription factor MYC with chromatin-associated protein host cell factor–1 controls expression of genes important for ribosome biogenesis and mitochondrial vigor, loss of which promotes tumor regression.

The novel Reach Cage allows neurophysiology studies of structured behavior with unrestrained Rhesus macaques showing that the frontoparietal reach network is selective for reach goals outside the immediately reachable space.

Small molecule inhibitors identified in a biophysical high-throughout screening assay confirm the importance of the interaction between single-stranded DNA and the protein RAD52 for the survival of BRCA2-depleted cells.

Dendrites combine the inputs that they receive from other neurons using calculations that have been optimized for those particular input patterns.

Gamma-band synchronization behavior in area V1 was predicted by weakly coupled oscillator principles.

Opposite neurons in multisensory areas compute the cue disparity information essential for information segregation.