268 results found
    1. Neuroscience

    Population rate-coding predicts correctly that human sound localization depends on sound intensity

    Antje Ihlefeld et al.
    Softer sound appears closer to midline than louder sound, conflicting with a labelled-line representation of auditory space and supporting the idea that humans use rate coding when calculating sound directionality.
    1. Neuroscience

    Decoding neural responses to temporal cues for sound localization

    Dan FM Goodman et al.
    Computer simulations of interaural time difference decoders show that heterogeneous tuning of binaural neurons leads to accurate sound localization in natural environments.
    1. Neuroscience

    Sound localization: These are not the neurons you are looking for

    Victor Benichoux, Daniel J Tollin
    Studies that looked into how the auditory brainstem processes the difference in the intensity of a sound as it reaches each ear may have wrongly assumed which neurons were being recorded.
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  1. Point of View: Five suggestions for substantial NIH reforms

    Michael Rosbash
    The National Institutes of Health needs to make radical changes to ensure that biomedical research continues to thrive in the United States.
    1. Human Biology and Medicine

    Point of View: Strategies from UW-Madison for rescuing biomedical research in the US

    Judith Kimble et al.
    A cross-campus, cross-career stage and cross-disciplinary series of discussions at a large public university has produced a series of recommendations for addressing the problems confronting the biomedical research community in the US.
    1. Neuroscience

    Thalamic reticular control of local sleep in mouse sensory cortex

    Laura MJ Fernandez et al.
    Local cortical sleep features arise subcortically due to heterogeneous burst discharge in neurons of a sleep rhythm pacemaker previously thought to act uniformly.
    1. Structural Biology and Molecular Biophysics

    Molecular basis of signaling specificity between GIRK channels and GPCRs

    Kouki K Touhara, Roderick MacKinnon
    A single kinetic step in the G protein activation cycle determines whether a G protein-coupled receptor activates G protein-gated K+ channels or not.
    1. Developmental Biology

    Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain

    Sylvie Remaud et al.
    Production of remyelinating subventricular zone oligodendrocyte progenitors is stimulated by transient abrogation of thyroid hormone signalling in the adult neural stem cell niche.
    1. Neuroscience

    Recruitment of inhibition and excitation across mouse visual cortex depends on the hierarchy of interconnecting areas

    Rinaldo David D'Souza et al.
    The relative recruitment of excitatory and inhibitory neurons by cortico-cortical interareal pathways depends on the hierarchy of areas and the laminar location of the neurons.

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