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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

    Hadar Cohen, Noam Baram ... Motti Gerlic
    A horizontally shared type VI secretion system affects the interaction between vibrios and eukaryotic hosts.
    1. Microbiology and Infectious Disease

    Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

    Shehryar Ahmad, Kara K Tsang ... John C Whitney
    A widespread family of chaperones functions to stabilize membrane protein effectors by mimicking transmembrane helical environments and promotes effector export by the bacterial type VI secretion system.
    1. Microbiology and Infectious Disease

    Type VI secretion system killing by commensal Neisseria is influenced by expression of type four pili

    Rafael Custodio, Rhian M Ford ... Rachel M Exley
    The upper airway commensal, Neisseria cinerea, competes with related species using a T6SS, with antagonism modulated by the spatial dynamics of attacker and prey strains growing in a mixed community.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Non-cognate immunity proteins provide broader defenses against interbacterial effectors in microbial communities

    Abigail Knecht, Denise Sirias ... Karine A Gibbs
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology

    Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System

    Zeng-Hang Wang, Ying An ... Tao Dong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
  1. Early-career researcher travel grants 2018: First seven authors selected

    The eLife travel grant programme offers up to $1000 to help recipients gain exposure and recognition for their work.
    1. Ecology
    2. Microbiology and Infectious Disease

    Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens

    Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
    12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
    Version of Record
    Short Report
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    NAIP–NLRC4-deficient mice are susceptible to shigellosis

    Patrick S Mitchell, Justin L Roncaioli ... Russell E Vance
    The NAIP-NLRC4 inflammasome in intestinal epithelial cells protects mice from oral route Shigella infection.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut

    Erik Bakkeren, Joana Anuschka Herter ... Wolf-Dietrich Hardt
    Bacterial gut pathogens that invade into host tissues during infection can boost the spread and accumulation of plasmids over time by forming reservoirs containing these plasmids within host tissues.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Dynamics of antimicrobial resistance and virulence of Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling