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    1. Medicine

    Adverse Drug Reactions: The benefits of data mining

    Audrey Bone, Keith Houck
    Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs.
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation

    Daniel R Fuentes et al.
    A new approach combines guide RNA multiplexing with CRISPR activation and interference to facilitate functional studies of transposable elements present in hundreds of copies throughout the human genome.
    1. Neuroscience

    Memory Formation: Let’s replay

    Björn Rasch
    Reactivating brain activity patterns during sleep enhances memory performance the next day.
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    1. Stem Cells and Regenerative Medicine

    Cystic Kidney Disease: Planarian ‘kidneys’ go with the flow

    Melanie Issigonis, Phillip A Newmark
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    1. Stem Cells and Regenerative Medicine

    Planaria: Genes for regeneration

    Janet Rossant
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Regulatory Networks: Reality check for transposon enhancers

    Julie Brind'Amour, Dixie L Mager
    Hundreds of retrovirus-like sequences have features that suggest they might be gene enhancers, but only a small fraction displays gene-regulating activity in experiments on mouse stem cells.
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    1. Neuroscience

    Electric Fish: Learning to generalize

    André Longtin
    Electric fish are able to take what they have learnt about sensory processing in certain situations and apply it in other situations.
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    1. Cancer Biology
    2. Medicine

    Science Forum: Challenges in validating candidate therapeutic targets in cancer

    Jeffrey Settleman et al.
    More than 30 published articles have suggested that a protein kinase called MELK is an attractive therapeutic target in human cancer, but three recent reports describe compelling evidence that it is not.