The HITS-CLIP sequencing method is used to demonstrate that cryptic exons can detect messenger RNA that contains nonsense mutations, and then cause this RNA to decay, which shows that these exons are involved in maintaining the electrical balance of neurons and, possibly, preventing epilepsy.

The cisternae of the Golgi contain two functionally distinct domains: the central areas, which remain stationary, and the edges or rims, which are mobile.

Cells that give rise to the infectious form of parasitic flatworms called schistosomes show similar patterns of gene expression to stem cells in free-living flatworms.

Structural analyses of the centriole proteins CPAP and STIL identify domains that are critical for centriole formation and provide a structural explanation for a mutation that causes human microcephaly.

A set of genes that are turned on only within time-limited windows—including genes encoding RNA binding molecules, let-7 microRNAs and IMP1—control developmental switches in stem cell properties between fetal development and adulthood.

Inflammatory monocytes carry live Mycobacteria from the lung to draining lymph nodes and acquire many characteristics of dendritic cells but fail to stimulate proliferation of CD4 T cells.

microRNA-1 plays an essential role in the development and functioning of the heart by ensuring that genes for striated, rather than smooth, muscle are expressed there.

A comprehensive and genome-wide description of the genomic make-up and frequency of meiotic recombination in Arabidopsis thaliana reveals regional preferences, including nucleosome-free regions, and two associated recombination motifs.

A signalling cascade involving PI3K/Akt1 remodels the extra-cellular matrix to achieve atypical cellular responses and control cell fate specification within the embryonic endoderm.

Long intergenic noncoding RNA molecules (lincRNAs) are shown to have critical roles in mammalian development and physiology in vivo.