4 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2+

    Jing Yong, Helmut Bischof ... Randal J Kaufman
    ATP enters the endoplasmic reticulum (ER) lumen through an SLC35B1/AXER-dependentCaATiER mechanism, and ATP usage in the ER renders 'anti-Warburg' effect by increasing ATP regeneration from OxPhos while decreasing glycolysis.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Phosphoregulation accommodates Type III secretion and assembly of a tether of ER-Chlamydia inclusion membrane contact sites

    Rachel J Ende, Rebecca L Murray ... Isabelle Derré
    To establish membrane contacts between its vacuole and the endoplasmic reticulum, the obligate intracellular bacterial pathogen Chlamydia trachomatis has evolved complex molecular strategies to mimic emerging regulatory processes that control contact-dependent organelle–organelle communication.
    1. Cell Biology

    OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway

    Jean-Claude Farre, Krypton Carolino ... Suresh Subramani
    The emerging importance of interorganellar communication is demonstrated by documentation of a feedback loop wherein peroxisome-generated metabolites affect mitochondrial ATP production and peroxisomal functions via signaling pathways requiring transmission of signals also through the cytosol and the nucleus.
    1. Cell Biology
    2. Developmental Biology

    Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

    Arian Mansur, Remi Joseph ... Vandana A Gupta
    Novel disease pathways underlie disease pathogenesis in Kelch-related nemaline myopathy through proteomic remodeling.

Refine your results by:

Type
Research categories