SLC35G1 is the first highly chloride-sensitive transporter localized on the basolateral membrane of intestinal epithelial cells, responsible for citrate absorption.
A high-phytate-low Ca2+ diet causes crystal nephropathies, renal phosphate wasting, and bone disease in rats, whereas high Ca2+ intake ameliorates the detrimental effects of a high-phytate diet.
A systemic hormone controls progenitor fate decisions independent of local fate determining pathways in the adult intestinal stem cell niche of Drosophila melanogaster..
Phosphate and calcium from resorbing bone can find their way to the coronary circulation and contribute to atherosclerotic calcification of the blood vessels.
Combining Organs-on-Chips technology with adult intestinal organoids provides an improved model of human duodenum and a new platform for preclinical drug assessment.
A new disposition mechanism for glucuronides, where liver serves as recycle organ and intestine serves as metabolism organ, is established to better explain the disposition of phenolics in vivo.
A novel multi-omics framework revealed the taxonomic contribution to microbiota oxalate, demontrated O. formigenes as the dominating taxon transcriptionally, and identified specific IBD cohort at risk for oxalte toxicity.