Calcium release from the endoplasmic reticulum through the IP₃ receptor ion channel is strongly regulated by a calcium-binding protein in the lumen of the endoplasmic reticulum.

Biochemically detailed modelling of pathways leading to post-synaptic plasticity reveals the dependence of neocortical LTP/LTD on the availability of different proteins and stimulation patterns.

Biochemical analysis reveals molecular mechanisms underlying the activation of the mitochondrial Ca²⁺ uniporter by intracellular Ca²⁺ signals.

Research into light-gated ion channels called channelrhodospins laid the foundations for the development of optogenetics, a technique that has gone on to revolutionize neuroscience.

In zebrafish larvae, it is the cell type that determines how the cell responds to a chemokine signal.

The feedback inhibition of T-type calcium channels by intracellular calcium provides new avenues to better decipher the roles of these low-voltage-activated channels in the fine control of calcium signaling events in physiology and pathophysiology.

Compartmentalized oscillations of second messengers affect global cellular signaling.

A native calcium ion channel has been identified in bacteria for the first time.

Starvation modulates thermotaxis behaviors in C. elegans via functional reconfiguration of a sensory network by gut-brain signaling.

Cryo-EM structures of human MCU-EMRE-MICU1-MICU2 complex in the apo and Ca²⁺-bound states reveal how MICU1 and MICU2 impart their gating function to the mitochondrial calcium uniporter.