The functional network of β-cells in the pancreatic islet, which has been used to identify important subpopulations of β-cells implicated in diabetes progression, is indicative of intrinsic dynamics rather than structural communication, implying islet robustness.

Intrinsic dynamics are shaped by the intersection of molecular, microstructural, connectomic, and activation gradients.

The rhythmicity in upper-limb tracking movements and associated population dynamics in primary motor cortex is explained by a feedback controller incorporating optimal state estimation.

Asymmetric localization of the receptor EGFR within branches of axons is required to establish the precise wiring of neuronal networks within the Drosophila brain.

There are fundamental limits to what can be learned about the origins of transcriptional noise from gene expression data alone, which can be overcome by simultaneously quantifying the abundances of linked molecular species.

Computational simulations and data analysis show that random clustering in the connections of neurons receiving minimal external cues can generate place fields and their spontaneous activation in trajectory-like sequences.

Electrophysiological study in human brain slices reveals that short-term synaptic plasticity from presynaptic pyramidal neuron to postsynaptic interneuron connections are target-cell specific based on their subclass interneuron identity.

Multimodal spectroscopy (smFRET, EPR, SAXS, and SANS) and integrative structural modeling reveal large-scale domain rearrangements in human guanylate binding protein 1 (hGBP1) that are driving forces for the formation of oligomers that enable its biological function in innate immune defense.

The dynamical transition between a protein and its surface water is decoupled.

Neuroimaging proves to be a powerful tool for capturing spatial and temporal dynamics across the whole nonhuman primate brain, bridging the gap between human and animal models.