2,150 results found
    1. Neuroscience

    Topographic gradients of intrinsic dynamics across neocortex

    Golia Shafiei et al.
    Intrinsic dynamics are shaped by the intersection of molecular, microstructural, connectomic, and activation gradients.
    1. Neuroscience

    Extrinsic and intrinsic dynamics in movement intermittency

    Damar Susilaradeya et al.
    The rhythmicity in upper-limb tracking movements and associated population dynamics in primary motor cortex is explained by a feedback controller incorporating optimal state estimation.
    1. Neuroscience

    Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling

    Marlen Zschätzsch et al.
    Asymmetric localization of the receptor EGFR within branches of axons is required to establish the precise wiring of neuronal networks within the Drosophila brain.
    1. Neuroscience

    Dynamic neuromuscular remodeling precedes motor-unit loss in a mouse model of ALS

    Éric Martineau et al.
    Motor axons undergo dynamic branch-specific changes for weeks before complete neuronal degeneration in a model of amyotrophic lateral sclerosis, highlighting the importance of peripheral factors, intrinsic and extrinsic to motoneurons.
    1. Neuroscience

    Motor selection dynamics in FEF explain the reaction time variance of saccades to single targets

    Christopher K Hauser et al.
    Oculomotor circuits are always busy planning the next eye movement, and this explains why, when a visual target appears, some eye movements toward it are produced very quickly whereas others take a long time to prepare.
    1. Neuroscience

    Recurrent circuit dynamics underlie persistent activity in the macaque frontoparietal network

    Eric Hart, Alexander C Huk
    Simultaneous recordings of neural ensembles in both the frontal and parietal cortices reveal how persistent activity can be maintained in the primate brain during visuospatial working memory.
    1. Neuroscience

    Atypical intrinsic neural timescale in autism

    Takamitsu Watanabe et al.
    Atypical intrinsic neural timescales in the sensory cortex and caudate were associated with local grey matter volume, and linked with the severity of autism.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

    Elliott D SoRelle et al.
    Single-cell RNA sequencing highlights the influence of host–pathogen interactions and stochasticity on transcriptional and phenotypic variance in lymphoblastoid cell lines derived from Epstein–Barr virus-infected primary B cells.
    1. Cell Biology
    2. Computational and Systems Biology

    Limits on information transduction through amplitude and frequency regulation of transcription factor activity

    Anders S Hansen, Erin K O'Shea
    The ability of cells to transmit information encoded in signaling dynamics is fundamentally limited by the gene decoding step.
    1. Computational and Systems Biology
    2. Neuroscience

    Stochastic and deterministic dynamics of intrinsically irregular firing in cortical inhibitory interneurons

    Philipe RF Mendonça et al.
    A-type potassium conductances influence the distinctive firing behaviour of irregular-spiking interneurons.

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