300 results found
    1. Neuroscience

    Atypical intrinsic neural timescale in autism

    Takamitsu Watanabe et al.
    Atypical intrinsic neural timescales in the sensory cortex and caudate were associated with local grey matter volume, and linked with the severity of autism.
    1. Neuroscience

    A hierarchy of timescales explains distinct effects of local inhibition of primary visual cortex and frontal eye fields

    Luca Cocchi et al.
    The selective effect of local inhibition on diffuse patterns of brain connectivity can be accounted for by an intrinsic hierarchical ordering of cortical timescales.
    1. Neuroscience

    Computational Psychiatry: Exploring atypical timescales in the brain

    Leonardo L Gollo
    Identifying activity imbalances in specific brain regions may help to diagnose and treat psychiatric disorders.
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    1. Neuroscience

    Lognormal firing rate distribution reveals prominent fluctuation–driven regime in spinal motor networks

    Peter C Petersen, Rune W Berg
    Neuronal participation in generation of motor patterns in the spinal circuits is lognormal, which is an indication of a rich diversity of activity within the mean-driven as well as the fluctuation-driven regimes.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Temporal profiling of redox-dependent heterogeneity in single cells

    Meytal Radzinski et al.
    Analysis of aging yeast cells using the in-vivo roGFP2-based probe reveals redox-dependent heterogeneity, reflected in a bi-modal distribution of the oxidation status, differential growth and replication, as well as distinct proteomic and transcriptomic profiles.
    1. Neuroscience
    2. Computational and Systems Biology

    Dynamic structure of locomotor behavior in walking fruit flies

    Alexander Y Katsov et al.
    A principled statistical segmentation of fruit fly walking leads to a compact model of immediate actions that can reproduce the unique behavioral sequences of individual flies.
    1. Neuroscience

    Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues

    Julieta E Lischinsky et al.
    Studying the development of the medial amygdala in the mouse reveals how the brain may potentially process sex differences in innate behaviors such as mating.
    1. Neuroscience

    Inhibitory peptidergic modulation of C. elegans serotonin neurons is gated by T-type calcium channels

    Kara E Zang et al.
    Genetic analysis of how neuropeptides control C. elegans reproductive behavior shows how T-type calcium channels engage and disengage target neurons from these critical regulators of neural circuits and behavior.
    1. Microbiology and infectious disease

    Asymmetric division triggers cell-specific gene expression through coupled capture and stabilization of a phosphatase

    Niels Bradshaw, Richard Losick
    Asymmetric cell division is linked to cell-specific transcription by handoff of a key developmental regulator from the cytokinetic machinery to the adjacent cell pole where it oligomerizes to become stabilized and activated.

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