Neuroimaging proves to be a powerful tool for capturing spatial and temporal dynamics across the whole nonhuman primate brain, bridging the gap between human and animal models.
Atypical intrinsic neural timescales in the sensory cortex and caudate were associated with local grey matter volume, and linked with the severity of autism.
Kenneth Wengler, Andrew T Goldberg ... Guillermo Horga
fMRI evidence for distinct hierarchical alterations in intrinsic neural timescales for different positive symptoms of schizophrenia support hierarchical perceptual-inference models of psychosis and suggest local increases in excitation-inhibition ratio.
Sensory-evidence accumulation is a distributed cortical computation, but frontal cortical areas contribute to accumulation on longer timescales than posterior cortical areas.
Richard Gao, Ruud L van den Brink ... Bradley Voytek
Invasive electrophysiological recording measures neuronal transmembrane current timescales across human cortex, which lengthens from sensory to association regions, follows variations in ion channel expressions, and alters with behavior and aging.
Vincent Fontanier, Matthieu Sarazin ... Emmanuel Procyk
Single unit recordings in monkeys and biophysical modelling demonstrate that local inhibitory-controlled metastable neural states specify the temporal organization of cognitive functions in frontal areas.
Simultaneous recordings of neural ensembles in both the frontal and parietal cortices reveal how persistent activity can be maintained in the primate brain during visuospatial working memory.
The selective effect of local inhibition on diffuse patterns of brain connectivity can be accounted for by an intrinsic hierarchical ordering of cortical timescales.
Ruben A Tikidji-Hamburyan, Gubbi Govindaiah ... Matthew T Colonnese
The imprecise and broad connectivity of retinal inputs during development have the potential to generate large correlations in target neurons that reduce retinotopic information unless suppressed by the special synaptic and circuit properties present at these ages.
A spiking neural network model explains how hippocampal theta sequences in two-dimensional arenas can arise from a combination of sensory-motor inputs, short-term synaptic plasticity, and intrinsic connectivity.
