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    1. Neuroscience

    A reservoir of timescales emerges in recurrent circuits with heterogeneous neural assemblies

    Merav Stern, Nicolae Istrate, Luca Mazzucato
    The large range of timescales empirically observed in neural circuits can be naturally explained when neural assemblies of heterogeneous size are recurrently coupled, empowering the neural circuits to efficiently process complex time-varying input signals.
    1. Developmental Biology
    2. Physics of Living Systems

    Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis

    Krishnan S Iyer, Chaitra Prabhakara ... Madan Rao
    An information theoretic and systems biology approach shows that cellular compartmentalisation and receptor promiscuity can facilitate the accurate and robust inference of position from noisy morphogen profiles, verified by experiments in Drosophila wing imaginal disc.
    1. Neuroscience

    Self-organized reactivation maintains and reinforces memories despite synaptic turnover

    Michael Jan Fauth, Mark CW van Rossum
    Despite ongoing rewiring and continuous turnover of synapses, a computational model shows that memories can maintain and even strengthen their connectivity by self-reactivating during periods without sensory input.
    1. Neuroscience

    Evolutionary shaping of human brain dynamics

    James C Pang, James K Rilling ... Luca Cocchi
    Human brains evolved to have neural dynamics that facilitate brain-wide integration supporting complex behavior.
    1. Neuroscience

    Integrating prediction errors at two time scales permits rapid recalibration of speech sound categories

    Itsaso Olasagasti, Anne-Lise Giraud
    Keeping flexible adaptable representations of speech categories at different time scales allows the brain to maintain stable perception in the face of varying speech sound characteristics.
    1. Computational and Systems Biology
    2. Neuroscience

    Fast and flexible sequence induction in spiking neural networks via rapid excitability changes

    Rich Pang, Adrienne L Fairhall
    Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.
    1. Neuroscience

    Velocity coupling of grid cell modules enables stable embedding of a low dimensional variable in a high dimensional neural attractor

    Noga Mosheiff, Yoram Burak
    The neural representation of position in the medial entorhinal cortex may be stabilized by synaptic connectivity across modules, which enforces coherent updates in their states.
    1. Neuroscience

    Computational Psychiatry: Exploring atypical timescales in the brain

    Leonardo L Gollo
    Identifying activity imbalances in specific brain regions may help to diagnose and treat psychiatric disorders.
    Version of Record
    Insight
    1. Neuroscience

    Spontaneous neural synchrony links intrinsic spinal sensory and motor networks during unconsciousness

    Jacob Graves McPherson, Maria F Bandres
    Persistent, non-random sensorimotor connectivity reveals the capacity of intrinsic spinal networks to purposefully replay and modify learned patterns of neural transmission during unconsciousness.
    1. Neuroscience

    Neural mechanisms underlying the temporal organization of naturalistic animal behavior

    Luca Mazzucato
    Naturalistic animal behavior exhibits a complex organization in the temporal domain, whose variability stems from hierarchical, contextual, and stochastic sources and can be naturally explained in terms of metastable attractor models.