A majority of transcribed transposons during aging are derived from transcriptional defects, most notably intron retention and transcriptional readthrough.

Biochemical, transcriptomic, and proteomic analyses reveal that protein arginine methyltransferases post-transcriptionally regulate intron detention—introns that persist in nuclear polyadenylated RNA—through methylation of RNA splicing and processing factors.

The 3'-end formation complex CFIm regulates S-adenosylmethionine (SAM) homeostasis by promoting the splicing of the SAM synthetase transcript, MAT2A.

High throughput sequencing of Arabidopsis mutants lacking the U6 snRNA methyltransferase FIONA1/METTL16 uncovers the role of U6 methylation in splicing signal preferences.

Partial copy loss of spliceosome genes are common non-driver gene dependencies in cancer.

Alternative splicing provides a mechanism to maintain oscillations of the circadian clock.

Rtf2 is shown to associate with multiple splicing factors and influence splicing of a subset of introns explaining why previous work erroneously assigned it as a replication restart factor in fission yeast.

RNA-binding protein SRSF3 mediates critical changes in RNA processing of pluripotency genes, which reveals functional consequences of regulated RNA processing during stem cell self-renewal and early development.