743 results found
    1. Genomics and Evolutionary Biology

    Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates

    Zachary Baker et al.
    PRDM9 is widely conserved across vertebrates yet has been lost numerous times, as has its role in directing meiotic recombination.
    1. Biochemistry and Chemical Biology
    2. Ecology

    De novo synthesis of a sunscreen compound in vertebrates

    Andrew R Osborn et al.
    Many vertebrates are able to synthesize a sunscreen compound de novo and the pathway involved can be used for heterologous production of the compound in yeast.
    1. Developmental Biology and Stem Cells

    Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species

    Ricardo Antonio Rosselló et al.
    Cells from vertebrate and invertebrate model systems can be reprogrammed into stem-like cells using mouse genes.
    1. Developmental Biology and Stem Cells

    Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ

    Hanh Thi-Kim Vu et al.
    Planarians provide evidence for a common evolutionary origin of vertebrate and invertebrate excretory systems and provide a novel experimental model to study human kidney diseases.
    1. Developmental Biology and Stem Cells
    2. Genomics and Evolutionary Biology

    Ancient origin of lubricated joints in bony vertebrates

    Amjad Askary et al.
    Zebrafish have lubricated joints similar to ours and are a tractable model for arthritis research.
    1. Developmental Biology and Stem Cells
    2. Genomics and Evolutionary Biology

    Evolution of the head-trunk interface in tetrapod vertebrates

    Elizabeth M Sefton et al.
    Both gill musculature and the evolutionarily conserved cucullaris muscle are derived from unsegmented mesoderm adjacent to the first 3 somites, extending the posterior limit of cranial mesoderm.
    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

    Hannah K Long et al.
    Islands of non-methylated DNA are shown to perform a similar epigenetic role in many different vertebrate species.
    1. Biophysics and Structural Biology
    2. Neuroscience

    Fundamental constraints in synchronous muscle limit superfast motor control in vertebrates

    Andrew F Mead et al.
    Vertebrate superfast muscles employ similar excitation–contraction strategies but distinct myosin heavy chain genes to allow superfast performance, revealing a maximum speed that cannot be overcome without sacrificing neural control.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection

    Don B Gammon et al.
    Novel virus-host systems yield insights into how Lepidopterans (moths and butterflies) combat RNA virus infection and reveal that poxvirus A51R proteins can suppress the host's immune system and stabilize microtubules in host cells.
    1. Ecology
    2. Genomics and Evolutionary Biology

    Heart fossilization is possible and informs the evolution of cardiac outflow tract in vertebrates

    Lara Maldanis et al.
    The discovery of a fossil heart in Rhacolepis buccalis demonstrates that it is possible to scrutinize the fossil record for important clues on cardiac structure and evolution.

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