86 results found
    1. Genetics and Genomics
    2. Neuroscience

    Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

    Jiro Yoshino, Sonali S. Mali ... Jay Z. Parrish
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice

    Amol Bhandare, Joseph van de Wiel ... Nicholas Dale
    Recordings from brainstem nuclei involved in chemosensory regulation of breathing in awake freely behaving mice show different complementary types of neuronal responses to hypercapnia in the retrotrapezoid nucleus and the rostral medullary raphe.
    1. Neuroscience

    Columnar neurons support saccadic bar tracking in Drosophila

    Giovanni Frighetto, Mark A Frye
    Flies have two parallel visual pathways with specialized physiological properties to compensate for perturbations in their flight course and to saccade toward objects.
    1. Microbiology and Infectious Disease

    A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi

    Noopur Dave, Ugur Cetiner ... Veronica Jimenez
    Structurally divergent bacterial-like mechanosensitive channels control multiple cellular functions in protozoan parasites.
    1. Neuroscience

    Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1

    Brianna Vandrey, Jack Armstrong ... Matthew F Nolan
    A synaptic circuit through which 'what' streams of information associated with the lateral entorhinal cortex may influence 'where' streams of information associated with the medial entorhinal cortex prior to their integration in the hippocampus.
    1. Cell Biology
    2. Neuroscience

    Intrinsic excitability mechanisms of neuronal ensemble formation

    Tzitzitlini Alejandre-García, Samuel Kim ... Rafael Yuste
    Optogenetic and electrical stimulation of primary visual cortex neurons reveals synaptic and cell-intrinsic mechanisms that underlie neuronal ensemble formation.
    1. Computational and Systems Biology

    Drift and termination of spiral waves in optogenetically modified cardiac tissue at sub-threshold illumination

    Sayedeh Hussaini, Vishalini Venkatesan ... Stefan Luther
    Excitability gradients in heart tissue, imposed by structured sub-threshold optogenetic stimulation, induce drift and termination of spiral waves, thus providing an explanation for successful optogenetic defibrillation in small animal hearts.
    1. Neuroscience

    Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision

    Silvia JH Park, Evan E Lieberman ... Joshua H Singer
    Anatomical and physiological analyses identified an inhibitory interneuron that is an integral part of the rod bipolar cell pathway, the circuit for night vision, of the mammalian retina.
    1. Neuroscience
    2. Physics of Living Systems

    Mathematical relationships between spinal motoneuron properties

    Arnault H Caillet, Andrew TM Phillips ... Luca Modenese
    Validated mathematical relationships between motoneuron morphometric and electrophysiological properties are provided as a tool for neuroscientists and modellers to generate hypotheses for experimental studies investigating currently unreported relationships and build virtual motoneuron profiles with consistent properties for modelling purposes.
    1. Neuroscience

    Dendritic NMDA receptors in parvalbumin neurons enable strong and stable neuronal assemblies

    Jonathan H Cornford, Marion S Mercier ... Dimitri M Kullmann
    NMDA receptors on PV+ interneurons mediate supralinear integration at feedback synapses from local pyramidal neurons, enabling competing networks to ‘lock’ onto salient inputs.

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