The mftG gene, present in the majority of mycofactocin gene clusters, encodes an oxidoreductase that facilitates ethanol utilization by reoxidation of mycofactocins and channeling electrons towards the respiratory chain.

A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation mechanisms.

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.