1,144 results found
    1. Cell Biology

    Cyclin-dependent kinase control of motile ciliogenesis

    Eszter K Vladar et al.
    Cyclin-dependentkinase 2 (Cdk2), the master regulator of S phase events during the cell cycle, controls the earliest step in the motile ciliogenesis pathway in quiescent multiciliatedairway epithelial cells.
  1. Peer Review Week 2018: eLife thanks reviewers for their contributions

    4,845 researchers reviewed 2,392 full submissions to eLife in the last year, helping to increase collaboration and transparency within the review process.
  2. eLife postcard propped up again point of sale display saying Ideas, with lightbulb-shaped jar in foreground

    Evaluating ideas for eLife’s Innovation Initiative

    We consider several questions before providing funding and mentorship for development of a new tool for open research communication.
    1. Microbiology and Infectious Disease

    Mechanistic Microbiome Studies: A Special Issue

    Curated by Wendy S Garrett et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the mechanistic understanding of microbiome function.
    1. Computational and Systems Biology
    2. Ecology

    Trade-off shapes diversity in eco-evolutionary dynamics

    Farnoush Farahpour et al.
    In a minimalistic, generic model of competitive communities in which evolution is constrained by life-history trade-offs, stable biodiversity emerges with species adapted to different functional niches.
  3. Annual report: Looking back on 2017

    A reflection on eLife's achievements in 2017, notably in convening and supporting communities, modernising technology for research communication and partnering with early-career researchers.
  4. From the eLife Board: More than just a journal

    Members of the eLife Board of Directors share their views on what we’ve achieved so far and where we’re going next.
    1. Cell Biology

    The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation

    Rengasayee Veeraraghavan et al.
    Structural and functional investigations identify a structural unit for ephaptic coupling in the heart, and provide the mechanistic basis for a novel strategy for the treatment of arrhythmias.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    The mobility of packaged phage genome controls ejection dynamics

    Alex Evilevitch
    Temperature and ionic conditions control the mechanical properties of virally encapsidated DNA and act as a switch between synchronized and desynchronized genome ejection dynamics in a phage population.
    1. Neuroscience

    A neural-level model of spatial memory and imagery

    Andrej Bicanski, Neil Burgess
    The BB model explains spatial cognition in terms of interactions between specific neuronal populations, providing a common computational framework for the human neuropsychological and in vivo animal electrophysiological literatures.

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