LMO2 plays an important role in the maintenance of T lymphocyte competence and survival of pre-thymic progenitors by regulating the expression of Bcl11a and Tcf7 genes.
In vitro reprogramming of human fibroblasts to Sertoli-like cells with immunosuppressive properties provides platforms for basic research and clinical application.
Histone deacetylase 1 (Hdac1) plays a crucial role in maintaining differential histone acetylation states of enhancers in various germ layers and regulates the transcriptional program both temporally and spatially.
The expression of the lipoprotein lipase (LPL) transporter GPIHBP1 in glioma capillaries promotes the LPL-mediated processing of triglyceride-rich lipoproteins, thereby providing lipid nutrients for glioma cells.
Multiple -omics approaches have provided valuable insight into the pathobiology of pediatric acute respiratory distress syndrome, and novel unbiased techniques hold promise for future discoveries.
Sujatha Jagannathan, Yuko Ogata ... Robert K Bradley
The myopathic transcription factor DUX4 induces discordant dysregulation of transcript and protein levels, demonstrating a key role for post-transcriptional gene regulation in facioscapulohumeral muscular dystrophy.
The physician involving the woman as much as she wants in her health care is significantly associated with up-to-date dual cervical and colorectal cancer screening compared to being up to date in only cervical cancer screening.
A transcriptome dataset of nearly 200 genetically identified mouse neuronal cell types revealed that short low-noise homeobox transcription factors and long neuronal effector genes best distinguish neuronal cell types.
