1,682 results found
    1. Developmental Biology

    Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease

    Daniyal J Jafree et al.
    Three-dimensional imaging was used to identify structural and quantitative features of developing lymphatics in the kidneys of mice, humans and in a genetic mouse model of polycystic kidney disease.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Gene Variation: The double-edged sword of evolution

    Etty Kruzel-Davila, Karl Skorecki
    Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.
    Insight
    Available as:
    • HTML
    • PDF
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

    Anneli Cooper et al.
    Common kidney disease risk variants in African populations are associated with reduced susceptibility to deadly African trypanosomes.
    1. Stem Cells and Regenerative Medicine

    Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ

    Hanh Thi-Kim Vu et al.
    Planarians provide evidence for a common evolutionary origin of vertebrate and invertebrate excretory systems and provide a novel experimental model to study human kidney diseases.
    1. Stem Cells and Regenerative Medicine

    Cystic Kidney Disease: Planarian ‘kidneys’ go with the flow

    Melanie Issigonis, Phillip A Newmark
    Insight
    Available as:
    • HTML
    • PDF
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Atypical calcium regulation of the PKD2-L1 polycystin ion channel

    Paul G DeCaen et al.
    Outward calcium ion currents desensitize the human PKD2-L1 ion channel via a mechanism that is independent of cytosolic motifs.
    1. Cancer Biology
    2. Cell Biology

    Inhibitor of ppGalNAc-T3-mediated O-glycosylation blocks cancer cell invasiveness and lowers FGF23 levels

    Lina Song, Adam D Linstedt
    The first inhibitor identified against an iso-enzyme that initiates O-glycosylation in the Golgi complex promises new therapeutic approaches for cancer and chronic kidney disease.
  1. Developing kidneys: an interview with Peter Hohenstein

    Originally from the Netherlands, Peter Hohenstein has been in Edinburgh since 2001 and now has his own group in The Roslin Institute, studying the link between normal kidney development and kidney disease. He is married and has a 4 year old daughter (and three cats), and he enjoys music, ‘mainly old stuff with lots of guitars’.
  2. Harnessing forces: an interview with Lining (Arnold) Ju

    On reading that the 21st century would be known as the century of biology, mechanical engineering graduate Lining (Arnold) Ju decided to pursue a PhD in biomedical engineering. He is currently a postdoc at the Heart Research Institute and a lecturer at the University of Sydney in Australia, where he studies how platelets sense mechanical forces and how problems in this process can lead to various blood diseases.

Refine your results by:

Type
Research categories