3D light-sheet imaging identifies the location and metabolic sensitivity of β-cell subpopulations that lead and coordinate islet Ca²⁺ oscillations.

The novel live-attenuated SARS-CoV-2 nasal vaccine candidate is highly safe, induces robust cellular and mucosal immunity, and generates long-lasting neutralizing antibody titers.

Further evidence in support of a new amyloid-independent hypothesis for the pathogenesis of Alzheimer's disease is provided, with an expanded set of Alzheimer-causing mutations in the protease that produces amyloid.

Membrane lipids are involved in the maturation and cytotoxicity of Parkinson's synphilin-1 inclusion bodies.

A novel 'torn bag mechanism' is described for the release of LC3 positive and negative small extracellular vesicles (exosomes) from amphiectosomes.

FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.