T cell progenitor homing into the thymus requires kindlin-3 to stabilize their adhesion to vascular integrin ligands when blood flow velocities and shear rates increase during development.

Kindlin-2 co-operates with talin to activate fibronectin-binding integrins on fibroblasts and subsequently induces cell spreading by recruiting paxillin to small, peripheral nascent adhesions.

Biochemical and genetic approaches reveal how the focal adhesion protein kindlin-2 controls the liver development and homeostasis by reducing inflammation.

New roles in anti-tumour immunity for the adhesion protein Kindlin-1 via regulation of cytokine secretion and T cell regulation.

Biochemical and cell biological data suggest a model of nascent integrin adhesion complex formation based on synergistic phase separation of pathways surrounding the focal adhesion kinase (FAK) and the adaptor protein p130Cas.

A novel two-step model for integrin activation primed by Cas during cell migration and spreading on multiple extracellular matrix ligands.

The action of the collagen receptor DDR2 in CAFs regulates Rap1-Talin1 mediated Integrin mechanotransduction in breast tumors to impact tumor stiffness and metastases.

Type XVII collagen, a transmembranous protein in basal keratinocytes, suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis.

Calcium influx stimulates formation of ER/plasma membrane contacts adjacent to focal adhesions, and lipid transfer at these sites is required for adhesion disassembly during cell migration.

Elongation of C. elegans embryos requires stiffness and force to be specifically oriented in a coordinated manner in different cells.