364 results found
    1. Structural Biology and Molecular Biophysics

    Structural model for differential cap maturation at growing microtubule ends

    Juan Estévez-Gallego, Fernando Josa-Prado ... Maria A Oliva
    The tubulin GTPase cycle structurally modulates the microtubule cap, causing lattice expansion, which is an intermediate state involved in phosphate release and regulatory signaling.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics

    Leonid Peshkin, Enrico Maria Daldello ... Catherine Jessus
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    Fluid mechanics of luminal transport in actively contracting endoplasmic reticulum

    Pyae Hein Htet, Edward Avezov, Eric Lauga
    The viscous hydraulics of contracting endoplasmic reticulum networks challenge common solute transport theories, suggesting the contraction of peripheral sheets as a plausible driving mechanism.
    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana C Costa, Blanca R Murillo ... Monica M Sousa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Signatures of transposon-mediated genome inflation, host specialization, and photoentrainment in Entomophthora muscae and allied entomophthoralean fungi

    Jason E Stajich, Brian Lovett ... Carolyn Elya
    Entomophthora muscae has one of the largest fungal genomes (1.03 Gb) owing to extensive proliferation of transposable elements.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Myosin V executes steps of variable length via structurally constrained diffusion

    David Hathcock, Riina Tehver ... D Thirumalai
    A theoretical model comprehensively describes the stepping dynamics of the motor protein myosin V, unraveling the significance of a recently discovered structural constraint on the angle between its lever arms.
    1. Cell Biology

    Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells

    Kathryn E Kistler, Tatjana Trcek ... Ruth Lehmann
    The scaffolding protein Oskar organizes two types of germ granules by phase transition within the same cell but with distinct morphologies, composition and biological functions.
    1. Genetics and Genomics
    2. Neuroscience

    Characterizing the Spatial Distribution of Dendritic RNA at Single Molecule Resolution

    Jihoon Kim, Jean G Rosario ... Junhyong Kim
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Automated cryo-EM structure refinement using correlation-driven molecular dynamics

    Maxim Igaev, Carsten Kutzner ... Helmut Grubmüller
    Correlation-driven molecular dynamics provides a fully automated and human-bias-free framework for quantitative interpretation of modern cryo-electron microscopy data.

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