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Structural Biology and Molecular Biophysics
Exploring conformational equilibria of a heterodimeric ABC transporter
M Hadi Timachi, Cedric AJ Hutter ... Enrica Bordignon
A heterodimeric exporter exhibits conformational equilibria in the presence of nucleotides, suggesting a unified mechanistic model for the conformational cycle of ABC exporters.
Structural Biology and Molecular Biophysics
Cell Biology
p53 Family Proteins: Damage limitation
Ivano Amelio, Gerry Melino
Structural Biology and Molecular Biophysics
Cell Biology
Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level
Daniel Coutandin, Christian Osterburg ... Volker Dötsch
p63 uses an intricate network of domain-domain interactions to control its function in long-term quality maintenance of resting oocytes.
Biochemistry and Chemical Biology
Imaging and energetics of single SSB-ssDNA molecules reveal intramolecular condensation and insight into RecOR function
Jason C Bell, Bian Liu, Stephen C Kowalczykowski
Individual SSB-ssDNA complexes undergo reversible condensation and de-condensation that is modulated by RecOR during recombination.
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