Transient transcriptome sequencing and kinetic modeling suggest how the kinetics and yield of RNA splicing are encoded in the human genome.

Variation in SARS-CoV-2 viral kinetics are partly explained by an individual's immune state and the infecting variant, but substantial interpersonal variation limits the reliability of isolation policies tailored to an individual's vaccination status.

A combined chemical genetics, proximity labeling, and ADP-ribose site mapping approach shows that PARP-7 mono-ADP-ribosylates immune-relevant proteins on cysteine amino acids.

In the plant circadian clock photoreceptor ZEITLUPE, evolutionarily selected residues distinguish photocycle kinetics and allosteric signal transduction pathways to permit proper circadian timing.

Three-dimensional digital reconstruction shows the temporal and palatal regions of stemward avialans are evolutionarily and functionally conservative, and the mixture of plesiomorphic cranial morphologies together with derived postcranial skeleton manifests the key role of mosaicism in early bird diversification.

Live quantitative monitoring of transcriptional bursting reveals that enhancers responding to different regulators use the same kinetic strategy to produce a complex composite pattern of developmental expression.

A theoretical framework for the growth of microtubules quantifies the roles of geometry, mechanics, kinetics and randomness and provides a phase diagram for dynamic instability in these self-assembled polymers.

Elimination of GABA_A receptors from the axon terminals of specific retinal bipolar cell types alters the sensitivity and kinetics of retinal output.

Direct measurements of trafficking kinetics between organelles of the secretory pathway suggest that lipid-driven membrane domains laterally sort proteins during membrane traffic.

A real-time, stopped-flow method, in combination with protein-induced fluorescence enhancement, Förster resonance energy transfer, and time-resolved fluorescence spectroscopy, reveals a kinetic framework for understanding Dicer as a complex molecular motor.