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Muscle synergies are able to identify muscular adaptation that results from feelings of joint instability, whereas tibiofemoral kinematics are sensitive for detecting acute instability events during functional activities.

The use of adequate statistics is demonstrated to be an essential prerequisite to derive conclusions on thermodynamics and kinetics from molecular simulations.

A light-controllable ligand is used to probe where in the signaling cascade T cells discriminate self from non-self.

Echolocating toothed whales can detect and react to sudden prey movements during close approaches with speeds similar to ultra-fast tracking responses in human vision.

Doves improve their wingbeat efficacy without elevating maximum pectoralis power by angling their wings mid-downstroke to efficiently generate aerodynamic force while simultaneously tensioning the supracoracoideus tendon to assist the upstroke.

Faster ligand-binding kinetics of integrin low-affinity states suggests that integrin binding to ligand and intracellular adapters and the actin cytoskeleton precedes their stabilization, together with tensile force, of the high-affinity, extended-open integrin conformation.

After developing a force-gliding assay with nanometer and piconewton precision, it is concluded that multiple kinesins driving a single cargo induces tension, resulting in smooth cargo transport, even with roadblocks.

Global gene expression analysis unravels the underlying mechanisms for distinct crude oil induced defects in Atlantic haddock eggs and larvae.

Environmental heterogeneity can dramatically reduce the efficacy of selection and alter the neutral evolutionary dynamics in microbial range expansions.

Direct control of ligand binding half-life with light shows that lifetime strongly affects T cell signaling.